Deep Mutational Scanning of the GPCR Rhodopsin Reveals Pleiotropic Mutational Effects and Their Roles in Modulating Light Sensitivity
Steven K. Chen, Jing Liu, Belinda S. W. Chang
The paper uses deep mutational scanning to study pleiotropic effects in rhodopsin, revealing how mutations impact multiple molecular phenotypes and shape light sensitivity.
Proceedings of the National Academy of Sciences · Oct 30, 2026Peer-reviewedEvolutionary Biology