Heli-SMACC: Helicase-targeting SMAll Molecule Compound Collection
Holli‐Joi Martin, Mohammad Anwar Hossain, James Wellnitz, Enes Kelestemur, Joshua E. Hochuli, Sumera Parveen, C.H. Arrowsmith, Timothy Mark Willson, Eugene N. Muratov, Alexander Tropsha
The paper curates a database of helicase inhibitors, Heli-SMACC, and tests selected compounds against SARS-CoV-2 NSP13 ATPase, finding twelve inhibitors with dose-response activity.
bioRxiv · Jul 4, 2024 · PreprintBioinformatics