ARID5B drives an inflammatory-to-destructive shift in pathologic fibroblast behavior
Angela E. Zou, Suppawat Kongthong, Gerald F.M. Watts, Cassandra L. Murphy, Madison L. Fairfield, Alisa A. Mueller, Michael B. Brenner
This study identifies ARID5B as a transcription factor that shifts inflammatory fibroblasts from an inflammatory to a destructive phenotype in arthritis.
bioRxiv · Aug 10, 2026 · PreprintImmunology