Unraveling the distinct motion bias of TrkA-NGF complex in NGFR100W-driven HSAN V disease
Zahed Bin Rahim, Md Abul Bashar, Nayan Dash, Supti Paul, Rimsha Ziad, Sarmistha Mitra, Raju Dash
This study uses molecular dynamics simulations to analyze how NGFR100W mutation affects the structural dynamics of the TrkA-NGF complex, revealing altered motion patterns linked to HSAN V disease mechanisms.
bioRxiv · Feb 27, 2025 · PreprintNeuroscience