Raju Dash

This study uses molecular dynamics simulations to analyze how NGFR100W mutation affects the structural dynamics of the TrkA-NGF complex, revealing altered motion patterns linked to HSAN V disease mechanisms.

This study identifies deleterious nonsynonymous variants in human islet amyloid polypeptide (IAPP) and shows how they alter its conformational dynamics, potentially contributing to type 2 diabetes and protein misfolding disorders.

This study identifies three deleterious SNPs in HSPB5 that disrupt the αB-crystallin domain's structure and function, contributing to proteotoxicity-related diseases.

This study identifies neuromodulators from Curcuma amada targeting Acetylcholinesterase using in silico methods, showing drug-likeness and potential therapeutic effects for neurodegenerative disorders.

This study shows that stigmasterol protects hippocampal neurons from hypoxia-reoxygenation injury by inducing mitophagy through LXRβ activation.

The paper identifies deleterious non-synonymous SNPs in the SMPX gene associated with hearing impairment using bioinformatics tools.