Author

Largess Barua

Jeonbuk National UniversityORCID 0000-0001-8436-8774Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Research Focus:protein folding & dynamics· 1 Assay:protein sequence· 1 Assay:proteomics· 1

Frequent Co-Authors

Raju DashiD· 2 shared Md Abul BashariD· 1 shared Md. Chayan AliiD· 1 shared Md. Mafizur RahmaniD· 1 shared Mst. Shanzeda Khatun· 1 shared Nayan Dash· 1 shared Sarmistha MitraiD· 1 shared Supti Paul· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiophysics

Raju DashORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintNov 16, 2024

Elucidating conformational alteration of human islet amyloid polypeptide by nonsynonymous substitution

Md Abul Bashar, Largess Barua, Supti Paul…·Raju Dash

This study identifies deleterious nonsynonymous variants in human islet amyloid polypeptide (IAPP) and shows how they alter its conformational dynamics, potentially contributing to type 2 diabetes and protein misfolding disorders.

1 citation

humanproteomics

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BioinformaticsbioRxivPreprintNov 12, 2024

Proteostasis Associated Variants in HSPB5 Destabilize the αB-crystallin Domain

Mst. Shanzeda Khatun, Md. Chayan Ali, Largess Barua…·Md. Mafizur Rahman

This study identifies three deleterious SNPs in HSPB5 that disrupt the αB-crystallin domain's structure and function, contributing to proteotoxicity-related diseases.

DOI 10.1101/2024.11.12.623266

humanprotein sequence

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