Author

Susan A. Shorter

University of Greenwich

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Neuroscience· 1

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

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Emma Coakley-YoungsiD· 1 shared Giulia Getti· 1 shared Marc L. FivaziD· 1 shared Medhavi Ranatunga· 1 shared Simon Richardson· 1 shared

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2022-2022 · peak 1/yr

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Emma Coakley-YoungsORCID

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Recent·Most cited

Autism-associated CHD8 keeps proliferation of human neural progenitors in check by lengthening the G1 phase of the cell cycle

Emma Coakley-Youngs, Susan A. Shorter, Medhavi Ranatunga, Simon Richardson, Giulia Getti, Marc L. Fivaz

This study shows that CHD8 haploinsufficiency in human neural progenitors shortens the G1 phase of the cell cycle, leading to increased proliferation and potential macrocephaly in autism.

Biology Open · Sep 15, 2022Peer-reviewedNeuroscience