Marc L. Fivaz

This study shows that early hyperexcitability in ALS patient-derived motor neurons drives mitochondrial hypermetabolism, which later leads to mitochondrial failure and neuron loss.

This study shows lithium reduces synaptic vesicle exocytosis and slows recycling in glutamatergic synapses, suggesting it modulates glutamate release in bipolar disorder.

This study shows that CHD8 haploinsufficiency in human neural progenitors shortens the G1 phase of the cell cycle, leading to increased proliferation and potential macrocephaly in autism.