NeuroscienceBiology OpenPeer-reviewed
Autism-associated CHD8 keeps proliferation of human neural progenitors in check by lengthening the G1 phase of the cell cycle
Emma Coakley-Youngs, Susan A. Shorter, Medhavi Ranatunga…·Marc L. Fivaz
This study shows that CHD8 haploinsufficiency in human neural progenitors shortens the G1 phase of the cell cycle, leading to increased proliferation and potential macrocephaly in autism.
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