Reprogramming the neuronal secretory and metabolic machinery using correctors for Alzheimer therapy
Won Jin Cho, Yutong Shang, Sushmita Patil, Xin Qi, Bhanu P. Jena
The paper demonstrates that peptide and small molecule inhibitors of ATAD3A oligomers can restore neuronal viability and reduce oxidative stress in Alzheimer's disease neurons.
bioRxiv · Nov 9, 2024 · PreprintNeuroscience