The structures of two intermediates en route to DNA repair within a (6-4) photolyase
Chao Yang, Qi Yu, Xiaodan Cao, Sven Falke, Jie Nan, Emma V. Beale, Henry N. Chapman, Dongping Zhong, Thomas J. Lane
The paper uses X-ray crystallography to observe intermediates in DNA repair by (6-4) photolyase, revealing an oxetane species and a hemi-cleaved intermediate.
bioRxiv · Nov 6, 2026 · PreprintBiochemistry