Author
Universität HamburgORCID 0000-0002-4655-1743Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Chao Yang, Qi Yu, Xiaodan Cao…·Thomas J. Lane
The paper uses X-ray crystallography to observe intermediates in DNA repair by (6-4) photolyase, revealing an oxetane species and a hemi-cleaved intermediate.
Anne Creon, Emilie Scheer, Patrick Y. A. Reinke…·Thomas J. Lane
The paper uses statistical crystallography to model correlated motions in SARS-CoV-2 Mpro and shows how dimerization affects catalytic activity through structural links.
Viviane Kremling, Sven Falke, Yaiza Fernández-García…·Janina Sprenger
The paper identifies ligands binding to the SARS-CoV-2 nsp10-16 complex using X-ray crystallography and reports their structures, providing insights for drug discovery.
Tek Narsingh Malla, Kara A. Zielinski, Luis Aldama…·Marius Schmidt
The paper uses MISC to study Sulbactam inhibition of M. tuberculosis BlaC, revealing heterogeneity, cooperativity, and conformational changes in atomic detail.