Specific deletion of interleukin-1 beta in microglia improves acute outcome and modulates neurogenesis after ischemic stroke
Alba Grayston, Margarida Baptista, Kelly Wemyss, Ruby Taylor, Grace Cullen, Syeda S. Jafree, Nadim Luka, Joshua R. Cox, Joanne Elizabeth Konkel, David Brough, Stuart McRae Allan, Emmanuel Pinteaux
This study shows that deleting microglial IL-1β improves acute stroke outcomes and modulates neurogenesis, with effects more pronounced in females.
Glia · May 28, 2026Peer-reviewedNeuroscience