Author

Alba Grayston

Manchester Academic Health Science CentreORCID 0000-0002-1466-0099Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

David BroughiD· 3 shared Stuart McRae AllaniD· 3 shared Emmanuel PinteauxiD· 2 shared Raymond WongiD· 2 shared Ádám DénesiD· 1 shared Ari WaismaniD· 1 shared Benjamin LlewellyniD· 1 shared Bianca De Leon· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersNeuroscience

David BroughORCID

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3 papers

Recent·Most cited

NeuroscienceGliaPeer-reviewedMay 28, 2026

Specific deletion of interleukin-1 beta in microglia improves acute outcome and modulates neurogenesis after ischemic stroke

Alba Grayston, Margarida Baptista, Kelly Wemyss…·Emmanuel Pinteaux

This study shows that deleting microglial IL-1β improves acute stroke outcomes and modulates neurogenesis, with effects more pronounced in females.

2 citationstop 4%

mouseexperimental assay

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ImmunologyBrain Behavior and ImmunityPeer-reviewedNov 20, 2025

Cerebral ischaemic stroke results in altered mucosal IgA responses and host-commensal microbiota interactions.

Madeleine E. D. Hurry, David A Posner, Raymond Wong…·Matthew R. Hepworth

This study shows that cerebral ischaemic stroke alters mucosal IgA responses and host-commensal microbiota interactions, leading to changes in intestinal microbiota composition.

6 citations

mouseproteomics

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NeurosciencebioRxivPreprintFeb 16, 2024

Selective deletion of interleukin-1 alpha in microglia does not modify acute outcome but regulates neurorepair processes after experimental ischemic stroke.

Eloïse Lemarchand, Alba Grayston, Raymond Wong…·Emmanuel Pinteaux

This study investigates the role of microglial-derived IL-1 in experimental ischemic stroke, finding it does not affect acute damage but influences neurorepair and functional recovery.

1 citation

mouseexperimental assay

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