Author

Emmanuel Pinteaux

Manchester Academic Health Science CentreORCID 0000-0002-9986-4401Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Alba GraystoniD· 2 shared David BroughiD· 2 shared Stuart McRae AllaniD· 2 shared Ádám DénesiD· 1 shared Benjamin LlewellyniD· 1 shared Blake OuvrieriD· 1 shared Eloïse LemarchandiD· 1 shared Freddie WebbiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersNeuroscience

Alba GraystonORCID

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2 papers

Recent·Most cited

Specific deletion of interleukin-1 beta in microglia improves acute outcome and modulates neurogenesis after ischemic stroke

Alba Grayston, Margarida Baptista, Kelly Wemyss, Ruby Taylor, Grace Cullen, Syeda S. Jafree, Nadim Luka, Joshua R. Cox, Joanne Elizabeth Konkel, David Brough, Stuart McRae Allan, Emmanuel Pinteaux

This study shows that deleting microglial IL-1β improves acute stroke outcomes and modulates neurogenesis, with effects more pronounced in females.

Glia · May 28, 2026Peer-reviewedNeuroscience

Selective deletion of interleukin-1 alpha in microglia does not modify acute outcome but regulates neurorepair processes after experimental ischemic stroke.

Eloïse Lemarchand, Alba Grayston, Raymond Wong, Miyako Rogers, Blake Ouvrier, Benjamin Llewellyn, Freddie Webb, Nikolett Lénárt, Ádám Dénes, David Brough, Stuart McRae Allan, Gregory Jaye Bix, Emmanuel Pinteaux

This study investigates the role of microglial-derived IL-1 in experimental ischemic stroke, finding it does not affect acute damage but influences neurorepair and functional recovery.

bioRxiv · Feb 16, 2024 · PreprintNeuroscience