Author

Sylvie Cosnier

Sanofi (France)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Frederico Nardi· 1 shared Géraldine Pénarier· 1 shared Jérôme Arigon· 1 shared Magali MathieuiD· 1 shared Marianne Duhamel· 1 shared Maysoun Shomali· 1 shared Monsif Bouaboula· 1 shared Rosalía Arrebola· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Frederico Nardi

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1 paper

Recent·Most cited

An NAMPT Inhibitor Decreases NAMPT Capture by an Antibody Directed against the 5-Phosphoribosyl-1-Pyrophosphate-Binding Loop: A Rational for an NAMPT Occupancy Assay

Maysoun Shomali, Sandrine Hilairet, Marianne Duhamel, Frederico Nardi, Thomas Bertrand, Magali Mathieu, Rosalía Arrebola, Géraldine Pénarier, Samir Jegham, Jérôme Arigon, Sylvie Cosnier, Monsif Bouaboula

This paper shows that an NAMPT inhibitor-RP adduct reduces NAMPT capture by an antibody targeting the PRPP-binding loop, enabling a method to assess NAMPT occupancy and correlate it with NAD levels and drug efficacy.

bioRxiv · Dec 11, 2024 · PreprintCancer Biology