Regulation of Aldosterone Secretion by Substance P and the NK1 Receptor in Aldosterone-Producing Adenomas
A.-G. Lopez, Céline Duparc, Sylvie Renouf, Margot D’Agostino, Kelly De Sousa, Laurence Amar, Guillaume Defortescu, Gilles Manceau, Jean‐Christophe Sabourin, Fabio Luiz Fernandes-Rosa, Maria‐Christina Zennaro, Tchao Méatchi, Gaël Nicolas, Estelle Louiset, Hervé Lefèbvre
This study investigates the role of Substance P and the NK1 receptor in aldosterone-producing adenomas, finding SP-positive nerve fibers and NK1R expression in most APA tissues and SP-induced aldosterone secretion.
Annales d Endocrinologie · Sep 16, 2025Peer-reviewedPhysiology