Author

Maria‐Christina Zennaro

InsermORCID 0000-0001-5449-9191Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1

Frequent Co-Authors

Fabio Luiz Fernandes-RosaiD· 3 shared Nicolò FaeddaiD· 3 shared Stéphanie BaroniD· 3 shared Bakhta FedlaouiiD· 2 shared Eric CamereriD· 2 shared Ilaria Del GaudioiD· 2 shared Isabelle Giscos-Douriez· 2 shared May FayadiD· 2 shared

Activity by Year

2025-2025 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersPhysiology

Fabio Luiz Fernandes-RosaORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Regulation of Aldosterone Secretion by Substance P and the NK1 Receptor in Aldosterone-Producing Adenomas

A.-G. Lopez, Céline Duparc, Sylvie Renouf, Margot D’Agostino, Kelly De Sousa, Laurence Amar, Guillaume Defortescu, Gilles Manceau, Jean‐Christophe Sabourin, Fabio Luiz Fernandes-Rosa, Maria‐Christina Zennaro, Tchao Méatchi, Gaël Nicolas, Estelle Louiset, Hervé Lefèbvre

This study investigates the role of Substance P and the NK1 receptor in aldosterone-producing adenomas, finding SP-positive nerve fibers and NK1R expression in most APA tissues and SP-induced aldosterone secretion.

Annales d Endocrinologie · Sep 16, 2025Peer-reviewedPhysiology

Sexually dimorphic interzonal crosstalk reshapes the adrenal cortex in response to pathophysiological challenges

Nicolò Faedda, Alaa B Abdellatif, Francesco Carbone, May Fayad, Bakhta Fedlaoui, Rita Chamoun, Romane L’Héritier, Ilaria Del Gaudio, Ourida Koual, Isabelle Giscos-Douriez, Stéphanie Baron, Ben Atkinson, Xiaomin Li, Linghui Kong, Yunling Xu, , Maria‐Christina Zennaro

This study shows that environmental factors like diet and dexamethasone induce sex-specific changes in adrenal cortex zones through cell lineage conversion and transcriptional reprogramming.

bioRxiv · Sep 5, 2025 · PreprintPhysiology

Modulation of calcium signaling on demand to decipher the molecular mechanisms of primary aldosteronism

Bakhta Fedlaoui, Teresa Cosentino, Zeina Reda Al Sayed, Rita Alexandre Coelho, Isabelle Giscos-Douriez, Nicolò Faedda, May Fayad, Jean‐Sébastien Hulot, Christopher J. Magnus, Scott M. Sternson, Simon Travers-Allard, Stéphanie Baron, David Pentón, Fabio Luiz Fernandes-Rosa, Maria‐Christina Zennaro, Sheerazed Boulkroun

This study establishes an adrenocortical cell model to modulate sodium entry and calcium signaling, revealing its role in aldosterone biosynthesis and PA development.

Hypertension · Feb 12, 2025Peer-reviewedPhysiology

Blood-borne sphingosine 1-phosphate maintains vascular resistance and cardiac function.

Ilaria Del Gaudio, Philippe Bonnin, Emilie Vessières, Estelle Robidel, Manuella Garcia, Coralyne Proux, Alexandre Boutigny, Véronique Baudrie, Hoa Thi Thuy Ha, Ludovic Couty, Nicolò Faedda, Nesrine Mebrek, Théo Morel, Anja Nitzsche, Stéphanie Baron, , Eric Camerer

This study shows that blood-borne sphingosine 1-phosphate (S1P) maintains vascular resistance and cardiac function through albumin-S1P and myocyte S1PR signaling in mice.

bioRxiv · Jan 15, 2025 · PreprintPhysiology