Fabio Luiz Fernandes-Rosa

This study investigates the role of Substance P and the NK1 receptor in aldosterone-producing adenomas, finding SP-positive nerve fibers and NK1R expression in most APA tissues and SP-induced aldosterone secretion.

This study shows that environmental factors like diet and dexamethasone induce sex-specific changes in adrenal cortex zones through cell lineage conversion and transcriptional reprogramming.

This study establishes an adrenocortical cell model to modulate sodium entry and calcium signaling, revealing its role in aldosterone biosynthesis and PA development.