Bioconversion of p-coumaric acid to cis,cis-muconic acid using an engineered A. baylyi ADP1 - E. coli co-culture
Suchismita Maiti, T Priyadharshini, Lars M. Blank, Guhan Jayaraman
This study engineers a co-culture of A. baylyi and E. coli to convert p-coumaric acid to cis,cis-muconic acid, achieving 18.55 mM ccMA with improved titres but highlighting metabolic pathway bottlenecks.
bioRxiv · Mar 7, 2026 · PreprintBioengineering