A majority of HIV persistence during antiretroviral therapy is due to infected cell proliferation
D. B. Reeves, E. R. Duke, T. A. Wagner, S. E. Palmer, A. M. Spivak, J. T. Schiffer
The paper uses ecological methods to show that most HIV-infected cells during ART arise from proliferation, not new infections, suggesting proliferation reduction could decrease the viral reservoir.
bioRxiv · Sep 7, 2018Immunology