Author

T. Abbas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. Dutta· 1 shared A. Ratan· 1 shared B. M. Paschal· 1 shared C. R. Hunt· 1 shared C. YANG· 1 shared D. Wotton· 1 shared J. Drake· 1 shared J. M. Larner· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperCancer Biology

A. Dutta

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3 papers

Recent·Most cited

Induction of PARP7 Creates a Vulnerability for Growth Inhibition by RBN2397 in Prostate Cancer Cells

C. YANG, K. Wierbilowicz, N. M. Dworak, S. Y. Bae, S. B. Tengse, N. Abianeh, J. Drake, T. Abbas, A. Ratan, D. Wotton, B. M. Paschal

This paper shows that inhibiting PARP7 with RBN2397 reduces prostate cancer cell growth through multiple mechanisms, including trapping PARP7 in the nucleus and affecting gene expression.

bioRxiv · Sep 2, 2022Cancer Biology

EccDNA formation is dependent on MMEJ, repressed by c-NHEJ pathway, and stimulated by DNA double-strand break

T. Paulsen, P. Malapati, R. Eki, T. Abbas, A. Dutta

This study quantifies eccDNA formation, showing it depends on MMEJ and is repressed by c-NHEJ, with increased levels from DNA breaks and during S-phase.

bioRxiv · Dec 3, 2020 · PreprintCancer Biology

ZEB1 is Required for NHEJ-Mediated DSB Repair in Euchromatin

T. L. Genetta, T. Abbas, R. Pandita, C. R. Hunt, T. Pandita, J. M. Larner

This study identifies ZEB1's role in promoting NHEJ-mediated DSB repair in euchromatin by interacting with 53BP1 and inducing pro-NHEJ chromatin modifications.

bioRxiv · May 13, 2020 · PreprintCancer Biology