Author

R. Pandita

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1

Frequent Co-Authors

A. Jones· 2 shared C. R. Hunt· 2 shared J. Ashton· 2 shared M. T. Milano· 2 shared N. Khazan· 2 shared R. K. Singh· 2 shared R. Moore· 2 shared T. Conley· 2 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

A. Jones

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

HP1β Chromo Shadow Domain facilitates H2A ubiquitination for BRCA1 recruitment at DNA double-strand breaks

T. Pandita, V. K. Charaka, S. Chakraborty, C.-L. Tsai, X. Wang, R. Pandita, J. Taineer, C. R. Hunt

This study identifies HP1β's chromo shadow domain as essential for promoting H2A ubiquitination and BRCA1 recruitment at DNA double-strand breaks to facilitate homologous recombination repair.

bioRxiv · Jan 11, 2022 · PreprintCell Biology

Targeting Vitamin-D receptor (VDR) by a small molecule antagonist MeTC7 inhibits PD-L1 but controls THMYCN neuroblastoma growth PD-L1 independently

R. K. Singh, K. Kim, R. B. Rowswell-Turner, J. N. Hansen, N. Khazan, A. Jones, U. Sivagnanalingam, Y. Teramoto, T. Goto, Y. Jian, N. Battaglia, T. Conley, V. Hovanesian, N. Yano, R. Pandita, , R. Moore

This study shows that MeTC7, a VDR antagonist, reduces PD-L1 expression in cancer cells and inhibits neuroblastoma growth independently of PD-L1.

bioRxiv · Aug 16, 2020 · PreprintCancer Biology

ZEB1 is Required for NHEJ-Mediated DSB Repair in Euchromatin

T. L. Genetta, T. Abbas, R. Pandita, C. R. Hunt, T. Pandita, J. M. Larner

This study identifies ZEB1's role in promoting NHEJ-mediated DSB repair in euchromatin by interacting with 53BP1 and inducing pro-NHEJ chromatin modifications.

bioRxiv · May 13, 2020 · PreprintCancer Biology

Septins disruption controls tumor growth and enhances efficacy of Herceptin

R. K. Singh, K. K. Kim, N. Khazan, R. B. Rowswell_Turner, C. Laggner, A. Jones, P. Srivastava, V. Hovanesian, L. Lamere, T. Conley, R. Pandita, C. Baker, J. R. Myers, E. Prichett, A. Awada, , R. Moore

The paper develops UR214-9, a compound that disrupts septin filaments in cancer cells, inhibiting growth of HER2+ tumors and enhancing Herceptin efficacy.

bioRxiv · Feb 19, 2020 · PreprintCancer Biology