Age-independent influence of hematopoietic stem and progenitor cell populations during hematopoietic reconstitution
F. Gotzhein, T. Aranyossy, L. Thielecke, T. Sonntag, V. Thaden, B. Fehse, I. Mueller, I. Glauche, K. Cornils
This study compares the impact of donor age on hematopoietic reconstitution using a murine HSCT model with a multicolor barcode system, showing HSCs and MPPs drive reconstitution regardless of age.
bioRxiv · Aug 5, 2020 · PreprintCell Biology