Author

L. Thielecke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Research Focus:clustering· 1 Assay:DNA methylation· 1

Frequent Co-Authors

I. Glauche· 2 shared K. Cornils· 2 shared A. Ardura-Fabregat· 1 shared A. Eugster· 1 shared A. Gerbaulet· 1 shared A. Krueger· 1 shared A. Shemer· 1 shared A. Volaski· 1 shared

Activity by Year

2018-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCell Biology

I. Glauche

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Age-independent influence of hematopoietic stem and progenitor cell populations during hematopoietic reconstitution

F. Gotzhein, T. Aranyossy, L. Thielecke, T. Sonntag, V. Thaden, B. Fehse, I. Mueller, I. Glauche, K. Cornils

This study compares the impact of donor age on hematopoietic reconstitution using a murine HSCT model with a multicolor barcode system, showing HSCs and MPPs drive reconstitution regardless of age.

bioRxiv · Aug 5, 2020 · PreprintCell Biology

Engrafted parenchymal brain macrophages differ from host microglia in transcriptome, epigenome and response to challenge

A. Shemer, J. Grozovski, T. Leng Tay, J. Tao, A. Volaski, P. Suess, A. Ardura-Fabregat, M. Gross, J.-S. Kim, E. David, L. Chappell-Maor, L. Thielecke, C. K. Glass, K. Cornils, M. Prinz, S. Jung

This study compares transcriptomes, epigenomes, and responses to challenge between engrafted HSC-derived brain macrophages and host microglia, finding persistent molecular and functional differences.

bioRxiv · Oct 27, 2018Immunology

Hematopoietic stem cells differentiate into restricted myeloid progenitors before cell division

T. Grinenko, A. Eugster, L. Thielecke, B. Ramasz, A. Krueger, S. Dietz, I. Glauche, A. Gerbaulet, M. von Bonin, O. Basak, H. Clevers, T. Chavakis, B. Wielockx

This study shows hematopoietic stem cells can differentiate into restricted progenitors without dividing or entering the S phase, indicating fate decisions are uncoupled from cell division.

bioRxiv · Jan 30, 2018Cell Biology