Ferroptosis is determined by chloride ions
D. Huang, Z. Dai, C. Wang, H. Mai, J. Zhao, L. Cao, S. Wang, Z. Dai, K. Xu, R. He, S. Zhu, Y. Chen, T. Bing, X. Zhu, T. G. Chew, J. Huang
This study identifies chloride ions as essential determinants of ferroptosis, showing that extracellular chloride levels influence lipid peroxidation and cell death.
bioRxiv · Feb 7, 2023 · PreprintCell Biology