A Critical Role for Perivascular Cells in Amplifying Viral Haemorrhage Induced by Dengue Virus Non-Structural Protein 1
Y. P. Cheung, V. Mastrullo, D. Maselli, T. Butsabong, P. Madeddu, K. Maringer, P. Campagnolo
This study shows that pericytes amplify NS1-induced vascular leakage in dengue by contact-independent paracrine signaling, highlighting their role in severe dengue pathogenesis.
bioRxiv · Feb 13, 2020Microbiology