Comparative Tn-Seq reveals common daptomycin resistance determinants in Staphylococcus aureus despite strain-dependent differences in essentiality of shared cell envelope genes
K. A. Coe, W. Lee, G. Komazin-Meredith, T. C. Meredith, Y. H. Grad, S. Walker
This paper uses Tn-Seq to compare gene essentiality across multiple S. aureus strains, identifying common resistance determinants and strain-dependent differences under daptomycin exposure.
bioRxiv · May 23, 2019Microbiology