Author

T. C. Theisen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Research Focus:clustering· 1 Research Focus:database / resource· 1 Approach:deep learning· 1

Frequent Co-Authors

J. C. Boothroyd· 3 shared A. Ferrel· 1 shared A. G. Mendoza· 1 shared A. M. Cygan· 1 shared M. W. Panas· 1 shared N. D. Marino· 1 shared S. R. Quake· 1 shared S. Rastogi· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 20 mutual co-author links

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3 shared papersMicrobiology

J. C. Boothroyd

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3 papers

Recent·Most cited

MicrobiologybioRxivDec 26, 2021

Transcriptional signatures of clonally derived Toxoplasma tachyzoites reveal novel insights into the expression of a family of surface proteins.

T. C. Theisen, J. C. Boothroyd

The paper examines SRS gene expression in clonally derived Toxoplasma tachyzoites and finds that expression patterns are variable and not consistently inherited.

DOI 10.1371/journal.pone.0262374

scRNA-seqexperimental assay

𝕏 PostBluesky

BioengineeringbioRxivFeb 16, 2020

A single-parasite transcriptional atlas of Toxoplasma gondii reveals novel control of antigen expression

Y. Xue, T. C. Theisen, S. Rastogi…·J. C. Boothroyd

This study constructs a single-parasite transcriptional atlas of Toxoplasma gondii using scRNA-seq, revealing novel control mechanisms of antigen expression and developmental transitions.

DOI 10.7554/elife.54129

scRNA-seqdeep learning

𝕏 PostBluesky

MicrobiologybioRxivDec 6, 2019

Co-immunoprecipitation with MYR1 identifies three additional proteins within the Toxoplasma parasitophorous vacuole required for translocation of dense granule effectors into host cells

A. M. Cygan, T. C. Theisen, A. G. Mendoza…·J. C. Boothroyd

The paper identifies three new proteins interacting with MYR1 in Toxoplasma that are essential for translocating effector proteins into host cells.

DOI 10.1128/msphere.00858-19

experimental assayhost-pathogen & immune response

𝕏 PostBluesky