Extremely potent pan-sarbecovirus neutralizing antibodies generated by immunization of macaques with an AS03-adjuvanted monovalent subunit vaccine against SARS-CoV-2
Y. Feng, M. Yuan, J. M. Powers, M. Hu, J. E. Munt, P. S. Arunachalam, S. R. Leist, L. Bellusci, L. E. Adams, S. Sundaramurthy, L. M. Shirreff, M. L. Mallory, T. D. Scooby, A. Moreno, D. T. OHagan, , B. Pulendran
This study identifies potent pan-sarbecovirus neutralizing antibodies from vaccinated macaques, showing broad neutralization against SARS-CoV-2 variants and related viruses.
bioRxiv · Jan 19, 2023 · PreprintImmunology