I. Wilson

Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire

This study immunized cows with HIV Env trimers to generate broadly neutralizing antibodies targeting the V2-apex, revealing ultralong CDRH3 antibodies outcompete shorter ones in the response.

Extremely potent pan-sarbecovirus neutralizing antibodies generated by immunization of macaques with an AS03-adjuvanted monovalent subunit vaccine against SARS-CoV-2

This study identifies potent pan-sarbecovirus neutralizing antibodies from vaccinated macaques, showing broad neutralization against SARS-CoV-2 variants and related viruses.

Quantifying multivariate genotype-by-environment interactions, evolutionary potential and its context-dependence in natural populations of the water flea, Daphnia magna.

The paper quantifies multivariate genotype-by-environment interactions in Daphnia magna and finds context-dependent evolutionary potential for food vs. temperature responses.

Single-component multilayered self-assembling nanoparticles presenting rationally designed glycoprotein trimers as Ebola virus vaccines

This study designs and tests Ebola virus vaccines using stabilized GP trimers displayed on nanoparticles, showing they induce neutralizing antibodies and enhance infection.

Insights into the salivary N-glycome of Lutzomyia longipalpis, vector of visceral leishmaniasis

This study characterizes the N-glycan profile of Lutzomyia longipalpis saliva, identifying oligomannose structures and a novel 144 Da modification.

Genome-wide changes in genetic diversity in a population of Myotis lucifugus affected by white-nose syndrome

The paper uses whole-genome sequencing to analyze genetic diversity changes in Myotis lucifugus before and after white-nose syndrome, finding increased divergence in a specific genomic region associated with thermoregulation.