Co-Occurrence of Enzyme Domains Guides the Discovery of an Oxazolone Synthetase
T. de Rond, J. E. Asay, B. S. Moore
The paper introduces CO-ED, a genome mining approach that identifies novel multifunctional enzymes by analyzing co-occurring enzyme domains, leading to the discovery of an oxazolone synthetase.
bioRxiv · Jun 11, 2020Biochemistry