Marginal Effects of Systemic CCR5 Blockade with Maraviroc on Oral Simian Immunodeficiency Virus Transmission to Infant Macaques
E. Brocca-Cofano, C. Xu, K. Wetzel, M. Cottrell, B. Policicchio, K. Raehtz, D. Ma, T. Dunsmore, G. Haret-Richter, K. Musaitif, B. F. Keele, A. D. Kashuba, R. Collman, I. Pandrea, C. Apetrei
This study evaluates the effectiveness of maraviroc in preventing oral SIV transmission to infant macaques, finding only marginal impact despite CCR5 blockade.
bioRxiv · Apr 11, 2018Immunology