Author

C. Apetrei

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 4 Approach:experimental assay· 3 Organism:rat· 3 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:CITE-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

I. Pandrea· 3 shared B. F. Keele· 2 shared C. Xu· 2 shared E. Kim· 2 shared A. D. Kashuba· 1 shared A. Ferrari· 1 shared A. Gambotto· 1 shared A. I. Murphy· 1 shared

Activity by Year

2016-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersImmunology

I. Pandrea

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Tetravalent SARS-CoV-2 S1 Subunit Protein Vaccination Elicits Robust Humoral and Cellular Immune Responses in SIV-Infected Rhesus Macaque Controllers

M. S. Khan, E. Kim, Q. Le Hingrat, A. Kleinman, A. Ferrari, J. C. Sammartino, E. Percivalle, C. Xu, S. Huang, T. W. Kenniston, I. Cassaniti, F. Baldanti, I. Pandrea, A. Gambotto, C. Apetrei

This study evaluates a tetravalent SARS-CoV-2 S1 subunit vaccine in SIV-infected rhesus macaques, showing robust humoral and cellular immune responses, including cross-reactivity against Omicron.

bioRxiv · Mar 15, 2023Immunology

New SHIVs and Improved Design Strategy for Modeling HIV-1 Transmission, Immunopathogenesis, Prevention and Cure

H. Li, S. Wang, F.-H. Lee, R. S. Roark, A. I. Murphy, J. Smith, C. Zhao, J. Rando, N. Chohan, Y. Ding, E. Kim, E. Lindemuth, K. J. Bar, I. Pandrea, C. Apetrei, , G. M. Shaw

This paper demonstrates that SHIVs with bulky aromatic amino acid substitutions at Env375 replicate efficiently in rhesus macaques and can be used for preclinical HIV vaccine testing.

bioRxiv · Jan 13, 2021Microbiology

Marginal Effects of Systemic CCR5 Blockade with Maraviroc on Oral Simian Immunodeficiency Virus Transmission to Infant Macaques

E. Brocca-Cofano, C. Xu, K. Wetzel, M. Cottrell, B. Policicchio, K. Raehtz, D. Ma, T. Dunsmore, G. Haret-Richter, K. Musaitif, B. F. Keele, A. D. Kashuba, R. Collman, I. Pandrea, C. Apetrei

This study evaluates the effectiveness of maraviroc in preventing oral SIV transmission to infant macaques, finding only marginal impact despite CCR5 blockade.

bioRxiv · Apr 11, 2018Immunology

Ancient hybridization and strong adaptation to viruses across African vervet monkey populations

H. Svardal, A. Jasinska, C. Apetrei, G. Coppola, Y. Huang, C. Schmitt, B. Jacquelin, M. Müller-Trutwin, G. Weinstock, P. Grobler, R. Wilson, T. Turner, W. Warren, N. Freimer, M. Nordborg

This study analyzes genome-wide polymorphism in vervet monkeys to reveal ancient hybridization and strong adaptation to viruses, particularly SIV, across African populations.

bioRxiv · Nov 22, 2016Evolutionary Biology