Author

T. F. Guclu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Approach:mechanistic / dynamical model· 1 Assay:proteomics· 1

Frequent Co-Authors

A. R. Atilgan· 3 shared C. ATILGAN· 3 shared E. Toprak· 1 shared I. K. Gaszek· 1 shared I. Kantarcioglu· 1 shared M. S. Yildiz· 1 shared N. Kocatug· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 17 mutual co-author links

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3 shared papersBiophysics

A. R. Atilgan

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Author profile →

3 papers

Recent·Most cited

Elucidating TolC Protein Dynamics: Structural Shifts Facilitate Efflux Mediated β-lactam Resistance

I. Kantarcioglu, I. K. Gaszek, T. F. Guclu, M. S. Yildiz, A. R. Atilgan, E. Toprak, C. ATILGAN

This study investigates TolC protein dynamics in Gram-negative bacteria, identifying structural shifts that facilitate β-lactam efflux and resistance, with implications for antibiotic design.

bioRxiv · Feb 22, 2024Biophysics

Dynamic Community Composition Unravels Allosteric Communication in PDZ3

T. F. Guclu, A. R. Atilgan, C. Atilgan

The paper uses community composition analysis from molecular dynamics simulations to study how point mutants and ligands affect PDZ3's binding dynamics and selectivity.

bioRxiv · Dec 30, 2020Biophysics

N-terminus of the third PDZ Domain of PSD-95 Orchestrates Allosteric Communication for Selective Ligand Binding

T. F. Guclu, N. Kocatug, A. R. Atilgan, C. ATILGAN

This study investigates how mutations in the N-terminus of PDZ3 affect ligand binding selectivity through molecular dynamics simulations and free energy calculations.

bioRxiv · Aug 24, 2020Biophysics