Author

T. H. Khoang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Assay:structural biology· 2 Approach:mechanistic / dynamical model· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

B. D. Freudenthal· 2 shared P. Agarwal· 2 shared T. M. Weaver· 2 shared L. M. Cortez· 1 shared M. T. Washington· 1 shared T. H. Click· 1 shared T. M. Washington· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 17 mutual co-author links

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2 shared papersBiochemistry

B. D. Freudenthal

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2 papers

Recent·Most cited

Mechanism of nucleotide discrimination by the translesion synthesis polymerase Rev1

T. M. Weaver, T. H. Click, T. H. Khoang, T. M. Washington, P. Agarwal, B. D. Freudenthal

This study investigates how Rev1 discriminates between nucleotides during translesion synthesis, showing structural differences in hydrogen bonding and sugar pucker when using dCTP versus rCTP.

bioRxiv · Dec 1, 2021Biochemistry

Visualizing Rev1 Catalyze Protein-template DNA Synthesis

T. M. Weaver, L. M. Cortez, T. H. Khoang, M. T. Washington, P. Agarwal, B. D. Freudenthal

This study uses time-lapse X-ray crystallography to visualize Rev1's mechanism of catalyzing protein-template DNA synthesis, revealing key steps in nucleotide incorporation and product release.

bioRxiv · Apr 10, 2020Biochemistry