Mechanism of nucleotide discrimination by the translesion synthesis polymerase Rev1
T. M. Weaver, T. H. Click, T. H. Khoang, T. M. Washington, P. Agarwal, B. D. Freudenthal
This study investigates how Rev1 discriminates between nucleotides during translesion synthesis, showing structural differences in hydrogen bonding and sugar pucker when using dCTP versus rCTP.
bioRxiv · Dec 1, 2021Biochemistry