CD40 and CD80/86 signaling in cDC1s mediate effective neoantigen vaccination and generation of antigen-specific CX3CR1+ CD8+ T cells in mice
T. Yamauchi, T. Hoki, T. Oba, K. Attwood, C. Xuefang, F. Ito
This study shows that CD40 and CD80/86 signaling in cDC1s enhances neoantigen vaccine efficacy and generates CX3CR1+ CD8+ T cells in mice.
bioRxiv · Jun 15, 2020Immunology