NONCANONICAL ELECTROMECHANICAL COUPLING MECHANISM OF AN HCN CHANNEL
G. Dai, T. K. Aman, F. DiMaio, W. N. Zagotta
The paper investigates the structural rearrangements in spHCN channels during activation and inactivation, revealing a noncanonical electromechanical coupling mechanism involving the A helix and cAMP binding.
bioRxiv · Jan 6, 2021 · PreprintBiophysics