Measuring intramolecular connectivity in long RNA molecules using two-dimensional DNA patch-probe arrays
T. K. Chiang, O. Kimchi, H. K. Dhaliwal, D. A. Villarreal, F. F. Vasquez, V. N. Manoharan, M. P. Brenner, R. F. Garmann
This paper introduces a method to measure intramolecular connectivity in long RNA molecules using DNA patch-probe arrays and validates it on STMV RNA, revealing coexisting global and local structures.
bioRxiv · Mar 12, 2023Biophysics