M. P. Brenner

Measuring intramolecular connectivity in long RNA molecules using two-dimensional DNA patch-probe arrays

This paper introduces a method to measure intramolecular connectivity in long RNA molecules using DNA patch-probe arrays and validates it on STMV RNA, revealing coexisting global and local structures.

Multiphase coexistence capacity in complex fluids

The paper investigates how molecular interactions influence multiphase coexistence in complex fluids and shows that phase capacity is limited by sequence length.

The assembly yield of complex, heterogeneous structures: A computational toolbox

The paper introduces a computational framework to predict assembly yields of complex structures by combining statistical mechanics with automatic differentiation, validated through simulations and applied to protein and colloidal systems.

Uncovering the mechanism for aggregation in repeat expanded RNA reveals a reentrant transition

This study develops a framework to predict RNA repeat aggregation by analyzing bonding and entropy, revealing reentrant transitions and sequence-dependent behavior.

Longitudinal analysis of invariant natural killer T cell activation reveals a cMAF-associated transcriptional state of NKT10 cells

The paper uses single-cell RNA-sequencing to analyze iNKT cell activation states over time, identifying a cMAF-associated transcriptional state in NKT10 cells.

Phase separation in fluids with many interacting components

This study models phase separation in complex fluid mixtures using random matrix theory and shows how interactions and dynamics influence the number of coexisting phases.

RNA structure prediction including pseudoknots through direct enumeration of states

This paper introduces a new RNA secondary structure prediction method that accurately predicts pseudoknots by combining a polymer physics model with exhaustive enumeration of possible structures.