Human condensin I and II drive extensive ATP-dependent compaction of nucleosome-bound DNA
M. Kong, E. Cutts, D. Pan, F. Beuron, T. Kaliyappan, C. Xue, E. Morris, A. Musacchio, A. Vannini, E. Greene
This study shows human condensin I and II compact nucleosome-bound DNA through ATP-dependent motor activity, forming reversible DNA loops without displacing nucleosomes.
bioRxiv · Jun 27, 2019Biochemistry