Author

T. Kanekiyo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Alam· 1 shared E. Tajkhorshid· 1 shared G. Bu· 1 shared J. R. Macyczko· 1 shared J. R. Thompson· 1 shared J. Zhao· 1 shared L. J. Lewis-Tuffin· 1 shared L. T. M. Le· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiophysics

A. Alam

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

APOE deficiency impacts neural differentiation and cholesterol biosynthesis in human iPSC-derived cerebral organoids

J. Zhao, T. C. Ikezu, W. Lu, J. R. Macyczko, Y. Li, L. J. Lewis-Tuffin, Y. A. Martens, Y. Ren, Y. Zhu, Y. Asmann, N. Taner, T. Kanekiyo, G. Bu

This study shows that APOE deficiency in human iPSC-derived cerebral organoids disrupts lipid homeostasis and affects cholesterol biosynthesis and neurogenesis.

bioRxiv · Jun 30, 2022Cell Biology

Capturing the interplay of membrane lipids and structural transitions in human ABCA7

L. T. M. Le, J. R. Thompson, S. Dehghanighahnaviyeh, S. Pant, P. X. Dang, T. Kanekiyo, E. Tajkhorshid, A. Alam

This study presents cryo-EM structures of human ABCA7 in open and closed states, revealing lipid interactions and conformational changes, supported by functional analysis and MD simulations.

bioRxiv · Mar 1, 2021Biophysics