Author

S. Dehghanighahnaviyeh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

E. Tajkhorshid· 2 shared A. Accardi· 1 shared A. Alam· 1 shared C. A. Ahern· 1 shared E. Fortea· 1 shared J. D. Galpin· 1 shared J. R. Thompson· 1 shared K. Lam· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiophysics

E. Tajkhorshid

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintJul 1, 2022

Backbone amides are key determinants of Cl- selectivity in CLC ion channels

L. Leisle, K. Lam, S. Dehghanighahnaviyeh…·A. Accardi

The paper shows that backbone amides in CLC channels are critical for Cl- selectivity, as replacing them with ester groups reduces ion discrimination.

DOI 10.1101/2022.07.01.498497

experimental assayprotein folding & dynamics

𝕏 PostBluesky

BiophysicsbioRxivMar 1, 2021

Capturing the interplay of membrane lipids and structural transitions in human ABCA7

L. T. M. Le, J. R. Thompson, S. Dehghanighahnaviyeh…·A. Alam

This study presents cryo-EM structures of human ABCA7 in open and closed states, revealing lipid interactions and conformational changes, supported by functional analysis and MD simulations.

DOI 10.15252/embj.2022111065

humancryo-EM

𝕏 PostBluesky