Pathogen protein modularity enables elaborate mimicry of a host phosphatase
H. Li, J. Wang, T. Kuan, B. Tang, L. Feng, J. Wang, Z. Cheng, J. Sklenar, P. Derbyshire, M. Hulin, Y. Li, Y. Zhai, Y. Hou, F. Menke, Y. Wang, W. Ma
The paper identifies a modular (L)WY-LWY motif in Phytophthora effectors that recruits host PP2A phosphatase, enabling phosphoprotein regulation through structural mimicry.
bioRxiv · May 5, 2023Plant Biology