Sterile triggers drive joint inflammation in TNF and IL-1beta dependent mouse arthritis models
A. Thiran, I. Petta, G. Blancke, M. Thorp, G. Plankaert, M. Jans, V. Andries, K. Barbry, T. Hochepied, C. Vanhove, E. Gracey, E. Dumas, T. Manuelo, I. Josipovic, G. van Loo, , L. Vereecke
This study shows that joint inflammation in TNF and IL-1beta mouse arthritis models occurs independently of the microbiota, while TNF-driven gut inflammation depends on it.
bioRxiv · Jan 31, 2023Immunology