Author

T. Hochepied

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. Beling· 1 shared A. Bird· 1 shared A. Liston· 1 shared A. Moudra· 1 shared A. Thiran· 1 shared B. Dermaut· 1 shared C. Asselman· 1 shared C. Bredow· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperCell Biology

A. Beling

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Author profile →

4 papers

Recent·Most cited

MeCP2 binds to methylated DNA independently of phase separation and heterochromatin organisation

R. Pantier, M. Brown, S. Han, K. Paton, S. Meek, T. Montavon, T. McHugh, D. A. Kelly, T. Hochepied, C. Libert, T. Jenuwein, T. Burdon, A. Bird

This paper shows MeCP2 binds methylated DNA without needing phase separation or heterochromatin, and its foci are rare in most mammals.

bioRxiv · May 9, 2023Cell Biology

Sterile triggers drive joint inflammation in TNF and IL-1beta dependent mouse arthritis models

A. Thiran, I. Petta, G. Blancke, M. Thorp, G. Plankaert, M. Jans, V. Andries, K. Barbry, T. Hochepied, C. Vanhove, E. Gracey, E. Dumas, T. Manuelo, I. Josipovic, G. van Loo, , L. Vereecke

This study shows that joint inflammation in TNF and IL-1beta mouse arthritis models occurs independently of the microbiota, while TNF-driven gut inflammation depends on it.

bioRxiv · Jan 31, 2023Immunology

Ring Finger Protein 213 Assembles into a Sensor for ISGylated Proteins with Antimicrobial Activity

F. Thery, L. Martina, C. Asselman, H. Repo, Y. Zhang, K. Sedeyn, G. D. Moschonas, C. Bredow, Q. W. Teo, J. Zhang, M. Vessely, K. Leandro, D. Eggermont, D. De Sutter, K. Boucher, , F. Impens

This study identifies RNF213 as an ISG15-interacting sensor that detects ISGylated proteins and exhibits broad antimicrobial activity against multiple pathogens.

bioRxiv · Jun 3, 2021Cell Biology

Context-dependent effects of IL-2 rewire immunity into distinct cellular circuits

C. E. Whyte, K. Singh, O. T. Burton, M. Aloulou, A. Moudra, C. P. Roca, F. J. Naranjo, F. Lombard-Vadnais, L. Kouser, T. Hochepied, T. Y. F. Halim, S. Schlenner, S. Lesage, J. Dooley, A. Liston

This study identifies context-dependent effects of IL-2 on immune circuits by rewiring its production sources in mice, revealing distinct cellular responses and potential adverse effects.

bioRxiv · Dec 18, 2020Immunology