Peroxisome counteracts oxidative stresses by suppressing catalase import via Pex14 phosphorylation
Y. Fujiki, K. Okumoto, M. E. Shermely, M. Natsui, H. Kosako, R. Natsuyama, T. Marutani
The paper shows that oxidative stress induces Pex14 phosphorylation, which reduces catalase import into peroxisomes, increasing cytosolic catalase and enhancing cell resistance to H2O2.
bioRxiv · May 1, 2020Cell Biology