T. Moyo-Gwete

This study investigates how different isotypes of the same HIV-neutralizing antibody achieve enhanced neutralization potency through distinct mechanisms involving hinge and CH1 regions.

This study compares three HIV MPER-targeting antibodies, showing that CAP206-CH12's dependence on a variable residue limits its neutralization breadth, unlike the conserved residue reliance of 4E10 and VRC42.01.

This study examines antibody responses to the SARS-CoV-2 501Y.V2 variant in patients hospitalized in early 2021, finding robust cross-reactivity against earlier variants and the 501Y.V3 variant.