ImmunologybioRxiv
Generation of Functional Human T Cell Development in NOD/SCID/IL2rγnull Humanized Mice Without Using Fetal Tissue: Application as a Model of HIV Infection and Persistence
C. Colas, O. Volodina, K. Beland…·E. Haddad
This paper introduces a new humanized mouse model using cord blood-derived CD34+ cells and pediatric thymic tissue that supports functional T cell development and HIV infection and persistence.
DOI 10.1016/j.stemcr.2023.01.003